Except for the birth episode (#120: "And Baby Makes Four, conclusion"), this is the only one with a scene featuring an actual baby as one of the twins - presumably the boy since the crib is trimmed in blue. (Episode #124: "Is This Trip Necessary? included an hallucination where one of them appeared as a baby alligator.)
The closing "wrong number" scene is a remake of the tag from the original pilot "Mr. Big".
The naming of the ambassador's assistant "Zachary" is an apparent reference to guest star Jonathan Harris's most famous role as Dr. Zachary Smith in the TV series Lost in Space. His appearance in this episode also marks a reunion with Don Adams as both had earlier co-starred in The Bill Dana Show. In a further coincidence, Julie Bennett, who plays Zachary, previously appeared in Episode #66: "Supersonic Boom", in which Dana had a cameo.